Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

DELE1/KIAA0141 Antikörper (N-Term)

Dieses Anti-DELE1/KIAA0141-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DELE1/KIAA0141 in WB, ELISA und IF. Geeignet für Human und Ratte.
Produktnummer ABIN6991710

Kurzübersicht für DELE1/KIAA0141 Antikörper (N-Term) (ABIN6991710)

Target

Alle DELE1/KIAA0141 (DELE1) Antikörper anzeigen
DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

Reaktivität

  • 8
  • 1
  • 1
  • 1
  • 1
Human, Ratte

Wirt

  • 6
  • 2
Kaninchen

Klonalität

  • 8
Polyklonal

Konjugat

  • 8
Dieser DELE1/KIAA0141 Antikörper ist unkonjugiert

Applikation

  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF)
  • Bindungsspezifität

    • 4
    • 2
    • 1
    N-Term

    Aufreinigung

    DELE Antibody is affinity chromatography purified via peptide column.

    Immunogen

    DELE antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human DELE. The immunogen is located within the first 50 amino acids of DELE.

    Isotyp

    IgG
  • Applikationshinweise

    DELE antibody can be used for detection of DELE by Western blot at 1 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    DELE Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    DELE antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    DELE1/KIAA0141 (DELE1) (DAP3 Binding Cell Death Enhancer 1 (DELE1))

    Andere Bezeichnung

    DELE

    Hintergrund

    DELE Antibody: DELE is a recently identified DAP3-binding protein that is thought to be important in the induction of death receptor-mediated apoptosis. Transfected cells that stably express DELE were found to be susceptible to apoptosis induction by TNF-α, and TRAIL, whereas reducing DELE expression by siRNA rescued these cells from apoptosis induction. Furthermore, the reduction of DELE expression also inhibited the activation of caspase-3, caspase-8 and caspase-9 following stimulation by TNF-α, anti-Fas, or TRAIL, indicating the importance of DELE in apoptosis mediated by death receptors.

    Gen-ID

    9812

    NCBI Accession

    NP_055588

    UniProt

    Q14154
Sie sind hier:
Chat with us!