TFEB Antikörper (C-Term)
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- Target Alle TFEB Antikörper anzeigen
- TFEB (Transcription Factor EB (TFEB))
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Bindungsspezifität
- AA 390-440, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TFEB Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- TFEB antibody is human specific. At least three isoforms of TFEB are known to exist.
- Aufreinigung
- TFEB antibody is affinity chromatography purified via peptide column.
- Immunogen
- Rabbit polyclonal TFEB antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TFEB. The immunogen is located within amino acids 390 - 440 of TFEB.
- Isotyp
- IgG
- Top Product
- Discover our top product TFEB Primärantikörper
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- Applikationshinweise
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TFEB antibody can be used for detection of TFEB by immunohistochemistry at 2.5 μ,g/mL.
Antibody validated: Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- TFEB antibody is supplied in PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,4 °C
- Informationen zur Lagerung
- TFEB antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- Target
- TFEB (Transcription Factor EB (TFEB))
- Andere Bezeichnung
- TFEB (TFEB Produkte)
- Hintergrund
- The Transcription factor EB (TFEB) is a member in the basic helix-loop-helix leucine zipper superfamily of transcription factors that is translocated in a subset of renal tumors (1,2). Recent studies have shown that lysosomal biogenesis is regulated by TFEB (3), which is in turn regulated by the mammalian target of rapamycin (mTOR) complex 1 (4). Other evidence suggests that TFEB coordinates the major steps of the autophagic pathway by driving the expression of autophagy and lysosomal genes (5).
- Gen-ID
- 7942
- NCBI Accession
- NP_009093
- UniProt
- P19484
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