Angiopoietin 2 Antikörper (C-Term)

Produktnummer ABIN6991651

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Angiopoietin 2 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Angiopoietin 2 Antikörper (C-Term) (ABIN6991651)

Target: Angiopoietin 2 (ANGPT2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiopoietin 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Angiopoietin 2 Antikörper

Bindungsspezifität: C-Term

Spezifität: At least three isoforms of ANGPT2 are known to exist, this antibody will detect all three isoforms.

Aufreinigung: ANGPT2 Antibody is affinity chromatography purified via peptide column.

Immunogen: ANGPT2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ANGPT2. The immunogen is located within the last 50 amino acids of ANGPT2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ANGPT2 antibody can be used for detection of ANGPT2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ANGPT2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ANGPT2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Angiopoietin 2

Target: Angiopoietin 2 (ANGPT2)

Andere Bezeichnung: ANGPT2

Hintergrund: ANGPT2 Antibody: Angiopoietin-2 (ANGPT2) is a member of the Ang family, a family of angiogenic factors that play major roles in angiogenesis during the development and growth of human cancers, but also during lymphangiogenesis. ANGPT2 is generally considered an antagonist of ANGPT1 and endothelial TEK tyrosine kinase (TIE-2, TEK). ANGPT2 disrupts the vascular remodeling ability of ANGPT1 and is thought to induce endothelial cell apoptosis, resulting in vessel regression. Expression of ANGPT2 has been linked to invasive and metastatic phenotypes of gliomas and other cancers.

Molekulargewicht: Predicted: 55 kDa

Observed: 58 kDa

Gen-ID: 285

NCBI Accession: NP_001138

UniProt: O15123

Pathways: RTK Signalweg