CD33 Antikörper (AA 180-230)

Produktnummer ABIN6991611

Produktdetails anti-CD33 Antikörper

Target: CD33

Bindungsspezifität: AA 180-230

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD33 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: At least three isoforms of CD33 are known to exist, this antibody will detect all three isoforms.

Aufreinigung: CD33 Antibody is affinity chromatography purified via peptide column.

Immunogen: CD33 antibody was raised against a 14 amino acid synthetic peptide near the center of human CD33. The immunogen is located within amino acids 180 - 230 of CD33.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CD33 antibody can be used for detection of CD33 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CD33 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CD33 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CD33

Target: CD33

Andere Bezeichnung: CD33 (CD33 Produkte)

Synonyme: SIGLEC-3 antikoerper, SIGLEC3 antikoerper, p67 antikoerper, Siglec-3 antikoerper, gp67 antikoerper, CD33 molecule antikoerper, CD33 antigen antikoerper, CD33 antikoerper, Cd33 antikoerper

Hintergrund: CD33 Antibody: CD33 is a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family that is highly expressed on myeloid progenitor cells. Assessment of CD33 expression is of great importance in the immunodiagnosis of acute leukemia, allowing distinction between myeloid and lymphoid origin, as CD33 is generally restricted to the myelomonocytic lineage. CD33 can associate with the protein-tyrosine phosphatases SHP-1 and SHP-2 and thus could modulate downstream signaling events associated with cell activation. Common variants of CD33 have been found to be associated with late-onset Alzheimer's disease.

Gen-ID: 945

NCBI Accession: NP_001763

UniProt: P20138