Strumpellin Antikörper (C-Term)

Produktnummer ABIN6991586

Der Kaninchen Polyklonal Anti-Strumpellin-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, Strumpellin in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Strumpellin Antikörper (C-Term) (ABIN6991586)

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Strumpellin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Strumpellin Antikörper

Bindungsspezifität: C-Term

Spezifität: Multiple isoforms of Strumpellin are known to exist.

Aufreinigung: Strumpellin Antibody is affinity chromatography purified via peptide column.

Immunogen: Strumpellin antibody was raised against a 19 amino acid synthetic peptide near the carboxy terminus of human Strumpellin. The immunogen is located within the last 50 amino acids of Strumpellin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Strumpellin antibody can be used for detection of Strumpellin by Western blot at 1 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Strumpellin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Strumpellin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Strumpellin

Target: Strumpellin (WASHC5) (WASH Complex Subunit 5 (WASHC5))

Andere Bezeichnung: Strumpellin

Hintergrund: Strumpellin Antibody: Strumpellin is a ubiquitously expressed, multi-transmembrane and spectrin-repeat-containing protein. It is named for Strumpell disease, a progressive upper-motor neurodegenerative disease termed hereditary spastic paraplegia (HSP). The Strumpellin gene maps to the eighth HSP locus (SPG8) on chromosome 8p24.13. Three families liked to this locus have mutations in the Strumpellin gene, rescue studies of zebrafish with decreased Strumpellin expression with Strumpellin mRNA containing these mutations showed impaired normal function of this protein. Recent studies suggest that Strumpellin may also be involved in protein aggregation diseases.

Gen-ID: 9897

NCBI Accession: NP_055661

UniProt: Q12768