UHRF1BP1L Antikörper (AA 980-1030)
Kurzübersicht für UHRF1BP1L Antikörper (AA 980-1030) (ABIN6991575)
Target
Alle UHRF1BP1L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 980-1030
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Spezifität
- At least two isoforms of UHRF1BP1L are known to exist, this antibody will recognize both isoforms. UHRF1BP1L antibody is predicted to not cross-react with UHRF1BP1
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Aufreinigung
- UHRF1BP1L Antibody is affinity chromatography purified via peptide column.
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Immunogen
- UHRF1BP1L antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1L. The immunogen is located within amino acids 980 - 1030 of UHRF1BP1L.
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Isotyp
- IgG
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Applikationshinweise
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UHRF1BP1L antibody can be used for detection of UHRF1BP1L by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.
Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- UHRF1BP1L Antibody is supplied in PBS containing 0.02 % sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,4 °C
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Informationen zur Lagerung
- UHRF1BP1L antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- UHRF1BP1L (UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L))
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Andere Bezeichnung
- UHRF1BP1L
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Hintergrund
- UHRF1BP1L Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.
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Gen-ID
- 23074
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NCBI Accession
- NP_055869
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UniProt
- A0JNW5
Target
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