UHRF1BP1L Antikörper (Middle Region)
Kurzübersicht für UHRF1BP1L Antikörper (Middle Region) (ABIN1450050)
Target
Alle UHRF1BP1L Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse.
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Aufreinigung
- Affinity chromatography purified via peptide column
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Immunogen
- 17 amino acid synthetic peptide near the center of Human UHRF1BP1L
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS containing 0.02 % Sodium Azide as preservative
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "ICBP90, a novel methyl K9 H3 binding protein linking protein ubiquitination with heterochromatin formation." in: Molecular and cellular biology, Vol. 28, Issue 2, pp. 705-17, (2008) (PubMed).
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- UHRF1BP1L (UHRF1 (ICBP90) Binding Protein 1-Like (UHRF1BP1L))
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Andere Bezeichnung
- UHRF1BP1L
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Hintergrund
- The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1-like (UHRF1BP1L) is closely related to UHRF1BP1, also known as ICBP90, a transcription and cell cycle regulator that specifically binds to the histone H3 N-terminal tail. While little is known of UHRF1BP1L, UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells, suggesting that UHRF1BP1L may also be involved in chromatin regulation and cell proliferation.Synonyms: KIAA0701, UHRF1-binding protein 1-like
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Gen-ID
- 23074
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NCBI Accession
- NP_055869
Target
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