UHRF1BP1 Antikörper (AA 890-940)

Produktnummer ABIN6991574

Der Kaninchen Polyklonal anti-UHRF1BP1 Antikörper wird verwendet zum Nachweis von UHRF1BP1 in Proben von Human und Maus. Er wurde validiert für ELISA, WB, IF und IHC (p).

Kurzübersicht für UHRF1BP1 Antikörper (AA 890-940) (ABIN6991574)

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UHRF1BP1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-UHRF1BP1 Antikörper

Bindungsspezifität: AA 890-940

Spezifität: UHRF1BP1 antibody is predicted to not cross-react with UHRF1BP1L

Aufreinigung: UHRF1BP1 Antibody is affinity chromatography purified via peptide column.

Immunogen: UHRF1BP1 antibody was raised against a 17 amino acid synthetic peptide near the center of human UHRF1BP1. The immunogen is located within amino acids 890 - 940 of UHRF1BP1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: UHRF1BP1 antibody can be used for detection of UHRF1BP1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: UHRF1BP1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: UHRF1BP1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu UHRF1BP1

Target: UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))

Andere Bezeichnung: UHRF1BP1

Hintergrund: UHRF1BP1 Antibody: The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.

Gen-ID: 54887

NCBI Accession: NP_060224

UniProt: Q6BDS2