UHRF1BP1 Antikörper (Middle Region)
Kurzübersicht für UHRF1BP1 Antikörper (Middle Region) (ABIN1450049)
Target
Alle UHRF1BP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Kreuzreaktivität (Details)
- Species reactivity (tested):Human, Mouse.
-
Aufreinigung
- Affinity chromatography purified via peptide column
-
Immunogen
- 17 amino acid synthetic peptide near the center of Human UHRF1BP1
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Konzentration
- 1.0 mg/mL
-
Buffer
- PBS containing 0.02 % Sodium Azide as preservative
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freezing and thawing.
-
Lagerung
- 4 °C/-20 °C
-
Informationen zur Lagerung
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- UHRF1BP1 (UHRF1 Binding Protein 1 (UHRF1BP1))
-
Andere Bezeichnung
- UHRF1BP1
-
Hintergrund
- The Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1 (UHRF1BP1), also known as ICBP90, is a transcription and cell cycle regulator. It specifically binds to the histone H3 N-terminal tail when methylated on K9 by two functional domains, a PHD finger that defines the binding specificity and an SRA (SET- and RING-associated) domain that promotes binding activity. UHRF1BP1 is required for proper heterochromatin formation in mammalian cells. Furthermore, UHRF1BP1 is thought to be a pivotal target for the ERK1/2 signaling pathway to control the proliferation of Jurkat T cells.Synonyms: ICBP90-binding protein 1, UHRF1 binding protein 1, Ubiquitin-like containing PHD and RING finger domains 1-binding protein 1
-
Gen-ID
- 54887
-
NCBI Accession
- NP_060224
Target
-