CD48 Antikörper (AA 90-140)

Produktnummer ABIN6991511

Der Kaninchen Polyklonal Anti-CD48-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CD48 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für CD48 Antikörper (AA 90-140) (ABIN6991511)

Target: CD48

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD48 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CD48 Antikörper

Bindungsspezifität: AA 90-140

Spezifität: Two isoforms of SLAMF2 are known to exist, this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.

Aufreinigung: SLAMF2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SLAMF2 antibody was raised against a 19 amino acid synthetic peptide near the center of human SLAMF2. The immunogen is located within amino acids 90 - 140 of SLAMF2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SLAMF2 antibody can be used for detection of SLAMF2 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SLAMF2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SLAMF2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CD48

Target: CD48

Andere Bezeichnung: SLAMF2

Hintergrund: SLAMF2 Antibody: The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.

Gen-ID: 962

NCBI Accession: NP_1769

UniProt: P09326