NLRP11 Antikörper (C-Term)

Produktnummer ABIN6991407

Produktdetails anti-NLRP11 Antikörper

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Aufreinigung: NALP11 Antibody is affinity chromatography purified via peptide column.

Immunogen: NALP11 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of human NALP11. The immunogen is located within the last 50 amino acids of NALP11.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NALP11 antibody can be used for detection of NALP11 by Western blot at 1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NALP11 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NALP11 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NLRP11

Target: NLRP11 (NLR Family, Pyrin Domain Containing 11 (NLRP11))

Andere Bezeichnung: NALP11 (NLRP11 Produkte)

Synonyme: CLR19.6 antikoerper, NALP11 antikoerper, NOD17 antikoerper, PAN10 antikoerper, PYPAF6 antikoerper, PYPAF7 antikoerper, NLR family pyrin domain containing 11 antikoerper, NLRP11 antikoerper

Hintergrund: NALP11 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP11 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP11, it has been suggested that it has been associated with Crohn's disease.

Gen-ID: 204801

NCBI Accession: NP_659444

UniProt: P59045

Pathways: Inflammasome