NLRP10 Antikörper (N-Term)

Produktnummer ABIN6991406

Der Kaninchen Polyklonal Anti-NLRP10-Antikörper wurde für ELISA, WB, IF und IHC (p) validiert. Er ist geeignet, NLRP10 in Proben von Human zu detektieren.

Kurzübersicht für NLRP10 Antikörper (N-Term) (ABIN6991406)

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP10 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-NLRP10 Antikörper

Bindungsspezifität: N-Term

Aufreinigung: NALP10 Antibody is affinity chromatography purified via peptide column.

Immunogen: NALP10 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of human NALP10. The immunogen is located within the first 50 amino acids of NALP10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: NALP10 antibody can be used for detection of NALP10 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: NALP10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: NALP10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu NLRP10

Target: NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))

Andere Bezeichnung: NALP10

Hintergrund: NALP10 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1β, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1β, processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.

Gen-ID: 338322

NCBI Accession: NP_789791

UniProt: Q86W26

Pathways: Inflammasome