Secernin 1 Antikörper (C-Term)

Produktnummer ABIN6991376

Der Kaninchen Polyklonal Anti-Secernin 1-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, Secernin 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Secernin 1 Antikörper (C-Term) (ABIN6991376)

Target: Secernin 1 (SCRN1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Secernin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-Secernin 1 Antikörper

Bindungsspezifität: AA 320-370, C-Term

Aufreinigung: SCRN1 Antibody is affinity chromatography purified via peptide column.

Immunogen: SCRN1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SCRN1. The immunogen is located within amino acids 320 - 370 of SCRN1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SCRN1 antibody can be used for detection of SCRN1 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SCRN1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SCRN1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Secernin 1

Target: Secernin 1 (SCRN1)

Andere Bezeichnung: SCRN1

Hintergrund: SCRN1 Antibody: SCRN1 was first identified as a cytosolic protein that is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.

Gen-ID: 9805

NCBI Accession: NP_001138985

UniProt: Q12765