UBA2 Antikörper (C-Term)

Produktnummer ABIN6991337

Produktdetails anti-UBA2 Antikörper

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Bindungsspezifität: AA 550-600, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Aufreinigung: SAE2 Antibody is affinity chromatography purified via peptide column.

Immunogen: SAE2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SAE2. The immunogen is located within amino acids 550 - 600 of SAE2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: SAE2 antibody can be used for detection of SAE2 by Western blot at 0.25 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 4 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: SAE2 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: SAE2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu UBA2

Target: UBA2 (SUMO1 Activating Enzyme Subunit 2 (UBA2))

Andere Bezeichnung: SAE2 (UBA2 Produkte)

Hintergrund: SAE2 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.

Gen-ID: 10054

NCBI Accession: NP_005490

UniProt: Q9UBT2