ESX Homeobox 1 Antikörper (AA 140-190)

Produktnummer ABIN6991271

Der Kaninchen Polyklonal Anti-ESX Homeobox 1-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, ESX Homeobox 1 in Proben von Human zu detektieren.

Kurzübersicht für ESX Homeobox 1 Antikörper (AA 140-190) (ABIN6991271)

Target: ESX Homeobox 1 (ESX1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESX Homeobox 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-ESX Homeobox 1 Antikörper

Bindungsspezifität: AA 140-190

Aufreinigung: ESX1 Antibody is affinity chromatography purified via peptide column.

Immunogen: ESX1 antibody was raised against a 19 amino acid synthetic peptide near the center of human ESX1. The immunogen is located within amino acids 140 - 190 of ESX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ESX1 antibody can be used for detection of ESX1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ESX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: ESX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu ESX Homeobox 1

Target: ESX Homeobox 1 (ESX1)

Andere Bezeichnung: ESX1

Hintergrund: ESX1 Antibody: Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.

Gen-ID: 80712

UniProt: Q8N693