ESX Homeobox 1 Antikörper (Center)

Produktnummer ABIN499804

Produktdetails anti-ESX Homeobox 1 Antikörper

Target: ESX Homeobox 1 (ESX1)

Bindungsspezifität: Center

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ESX Homeobox 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: ESX1 antibody was raised against a 19 amino acid peptide near the center of human ESX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store the antibody (in aliquots) at -20 °C.

Details zu ESX Homeobox 1

Target: ESX Homeobox 1 (ESX1)

Andere Bezeichnung: ESX1 (ESX1 Produkte)

Synonyme: ESX1L antikoerper, ESXR1 antikoerper, Spx1 antikoerper, ESX homeobox 1 antikoerper, extraembryonic, spermatogenesis, homeobox 1 antikoerper, ESX1 antikoerper, Esx1 antikoerper

Hintergrund: Homeobox proteins are transcription factors that contain a helix-turn-helix DNA binding domain termed the homeodomain. ESX1 is an X-linked homeobox gene primarily expressed in the placenta and testis and contains two functional domains: the homeodomain and the proline-rich domain. During embryogenesis, ESX1 is expressed in the extraembryonic tissues, including the endoderm of the visceral yolk sac, the ectoderm of the chorion and the labyrinthine trophoblast of the chorioallantoic placenta. ESX1 can act like a transcriptional repressor to the human oncogene K-ras and treatment of human cancer cells with an ESX1 protein fragment containing the homeodomain reduces the tumorgenicity of cells containing oncogenic K-ras mutations, suggesting ESX1 may be useful as a therapeutic treatment for these cancers.Synonyms: ESX1L, ESX1R, Homeobox protein ESX1

Gen-ID: 80712

UniProt: Q8N693