EPH Receptor A10 Antikörper (N-Term)

Produktnummer ABIN6991150

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch EPH Receptor A10 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für EPH Receptor A10 Antikörper (N-Term) (ABIN6991150)

Target: EPH Receptor A10 (EPHA10)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPH Receptor A10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-EPH Receptor A10 Antikörper

Bindungsspezifität: AA 120-170, N-Term

Aufreinigung: EphA10 Antibody is affinity chromatography purified via peptide column.

Immunogen: EphA10 antibody was raised against a 14 amino acid synthetic peptide of near the amino terminus of human EphA10. The immunogen is located within amino acids 120 - 170 of EphA10.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: EphA10 antibody can be used for detection of EphA10 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: EphA10 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: EphA10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu EPH Receptor A10

Target: EPH Receptor A10 (EPHA10)

Andere Bezeichnung: EphA10

Hintergrund: EphA10 Antibody: Eph receptors, the largest subfamily of receptor tyrosine kinases (RTKs), and their ephrin ligands are important mediators of cell-cell communication regulating cell attachment, shape, and mobility of neuronal and endothelial cells in central nervous system function and in development. Eph receptors can be divided into two subgroups: EphA and EphB. In mammals, the EphA class consists of eight members (EphA 1-7 and 10) that in general bind to ephrin-A members linked to the cell membrane through a glycosylphosphatidylinositol linkage. The EphB class consists of six members (EphB 1-6) that in general bind ephrin-B members that transverse the cell membrane. The Ephrin / EPH signaling pathway networks with the WNT signaling pathway during embryogenesis, tissue regeneration, and carcinogenesis. Recent studies show that Eph/EFN might be relevant in normal B-cell biology and could represent new potential prognostic markers and therapeutic targets for CLL.

Gen-ID: 284656

NCBI Accession: NP_001092909

UniProt: Q5JZY3

Pathways: RTK Signalweg