PERP Antikörper (C-Term)

Produktnummer ABIN6991120

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PERP in WB, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PERP Antikörper (C-Term) (ABIN6991120)

Target: PERP (TP53 Apoptosis Effector (PERP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PERP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-PERP Antikörper

Bindungsspezifität: C-Term

Aufreinigung: PERP Antibody is affinity chromatography purified via peptide column.

Immunogen: Anti-PERP antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human PERP. The immunogen is located within the last 50 amino acids of PERP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1-2 μ,g/mL, ICC: 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PERP Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PERP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PERP

Target: PERP (TP53 Apoptosis Effector (PERP))

Andere Bezeichnung: PERP

Hintergrund: PERP Antibody: The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently. PERP, also termed PIGPC1 and THW, is a plasma membrane protein. p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis. The expression of PERP causes cell death. PERP is a mediator of p53 induced apoptosis. PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.

Molekulargewicht: Predicted: 21kD

Observed: 21 kD kDa

Gen-ID: 64058

NCBI Accession: NP_071404

UniProt: Q9JK95

Pathways: Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity