PERP Antikörper (Middle Region)
Kurzübersicht für PERP Antikörper (Middle Region) (ABIN2783850)
Target
Alle PERP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- PERP Antibody - middle region
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Sequenz
- FLRVIGGLLA LAAVFQIISL VIYPVKYTQT FTLHANPAVT YIYNWAYGFG
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Homologie
- Cow: 86%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PERP. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PERP
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49688-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PERP (TP53 Apoptosis Effector (PERP))
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Andere Bezeichnung
- PERP
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Hintergrund
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Background Information: PERP is a component of intercellular desmosome junctions. PERP plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. PERP also plays a role as an effector in the TP53-dependent apoptotic pathway.
Gene Name: PERP, TP53 apoptosis effector
Alternative Symbols: THW, KCP1, EKVP7, OLMS2, PIGPC1, KRTCAP1, dJ496H19.1
Protein Name: p53 apoptosis effector related to PMP-22
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Molekulargewicht
- 21kDa
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Gen-ID
- 64065
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NCBI Accession
- NP_071404
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UniProt
- Q96FX8
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Pathways
- Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity
Target
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