RUNX1 Antikörper (AA 160-210)

Produktnummer ABIN6991109

Der Kaninchen Polyklonal Anti-RUNX1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, RUNX1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für RUNX1 Antikörper (AA 160-210) (ABIN6991109)

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RUNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-RUNX1 Antikörper

Bindungsspezifität: AA 160-210

Aufreinigung: RUNX1 Antibody is affinity chromatography purified via peptide column.

Immunogen: RUNX1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RUNX1. The immunogen is located within amino acids 160 - 210 of RUNX1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RUNX1 antibody can be used for detection of RUNX1 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RUNX1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RUNX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Andere Bezeichnung: RUNX1

Hintergrund: RUNX1 Antibody: RUNX1 is one of three mammalian RUNX genes that control multiple aspects of embryonic development and are responsible for the pathogenesis of many human diseases. RUNX1 plays major roles in the development of nociceptive sensory neurons in addition to hematopoietic stem cells (HSC) with the exception of the erythroid lineage. During development, Notch signals mediate RUNX1 induction with SCL/GATA/Ets factors, and Wnt signals potentially cooperate with RUNX1 to facilitate adult HSC expansion via cooperative induction of cyclin D, cdk4, and other cell cycle regulators. In turn, RUNX1 regulates cell cycle transitions dependent on functional/physical interactions with other proteins such as HDAC1 and -3, mSin3A, p300, SMAD proteins, and LEF/TCF.

Gen-ID: 861

UniProt: Q01196