alpha Tubulin Antikörper (N-Term)

Produktnummer ABIN6991087

Dieses Huhn Polyklonal-Antikörper erkennt spezifisch alpha Tubulin in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für alpha Tubulin Antikörper (N-Term) (ABIN6991087)

Target: alpha Tubulin (TUBA1)

Reaktivität: Human, Maus, Ratte

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser alpha Tubulin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-alpha Tubulin Antikörper

Bindungsspezifität: AA 140-190, N-Term

Aufreinigung: Alpha-tubulin Antibody is affinity chromatography purified via peptide column.

Immunogen: Tubulin antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human Tubulin. The immunogen is located within amino acids 140 - 190 of Alpha-tubulin.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: Tubulin antibody can be used for detection of Tubulin by Western blot at 0.5 - 1 μ,g/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Alpha-tubulin Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Alpha-tubulin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu alpha Tubulin

Target: alpha Tubulin (TUBA1)

Andere Bezeichnung: Alpha-tubulin

Hintergrund: Alpha-tubulin Antibody: Alpha-tubulin belongs to the tubulin superfamily, which is composed of six distinct families. Along with beta-tubulins, alpha-tubulins are the major components of microtubules. These microtubules are involved in a wide variety of cellular activities ranging from mitosis and transport events to cell movement and the maintenance of cell shape. Alpha- and beta-tubulin dimers are assembled to 13 protofilaments that form a microtubule of 22-nm diameter. Tyrosine ligase adds a C-terminal tyrosine to monomeric alpha-tubulin. Assembled microtubules can again be detyrosinated by a cytoskeleton-associated carboxypeptidase. Another post-translational modification of detyrosinated alpha-tubulin is C-terminal polyglutamylation, which is characteristic of microtubules in neuronal cells and the mitotic spindle. Like GAPDH and beta-Actin, this antibody makes an excellent loading control in immunoblots.

Gen-ID: 7278

NCBI Accession: NP_005992

UniProt: Q13748

Pathways: Microtubule Dynamics