HINT1 Antikörper

Produktnummer ABIN6990986

Der Kaninchen Polyklonal Anti-HINT1-Antikörper wurde für WB, ELISA und ICC validiert. Er ist geeignet, HINT1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für HINT1 Antikörper (ABIN6990986)

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HINT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-HINT1 Antikörper

Aufreinigung: HINT1 Antibody is affinity chromatography purified via peptide column.

Immunogen: HINT1 antibody was raised against a 17 amino acid synthetic peptide near the center of the human HINT1. The immunogen is located within the last 50 amino acids of HINT1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: HINT1 antibody can be used for detection of HINT1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2.5 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: HINT1 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: HINT1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu HINT1

Target: HINT1 (Histidine Triad Nucleotide Binding Protein 1 (HINT1))

Andere Bezeichnung: HINT1

Hintergrund: HINT1 Antibody: Histidine triad nucleotide-binding protein 1 (HINT1) is a member of the histidine triad (HIT) protein family, a group of small nucleotide-binding and -hydrolyzing proteins. HINT1 interacts with several diverse proteins and has been suggested to have tumor suppressive activities. HINT1 catalyzes the hydrolysis of adenosine 5'-monophoramidate substrates such as AMP-morpholidate, but its enzymatic function does not appear to play a role in its tumor suppression. Recent experiments demonstrate that HINT1 forms a complex with POSH and JNK in vivo, inhibiting AP-1 activity and the phosphorylation of c-Jun, and this action could contribute to the tumor suppressor activity of HINT1. Other studies raise the possibility of HINT1 as a candidate gene for schizophrenia.

Gen-ID: 3094

NCBI Accession: NP_005331

UniProt: P49773