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NANOS2 Antikörper (N-Term)

Dieses Anti-NANOS2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NANOS2 in ELISA, WB, IHC (p) und IF. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN6990924

Kurzübersicht für NANOS2 Antikörper (N-Term) (ABIN6990924)

Target

Alle NANOS2 Antikörper anzeigen
NANOS2 (Nanos Homolog 2 (NANOS2))

Reaktivität

  • 32
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 29
  • 3
Kaninchen

Klonalität

  • 31
  • 1
Polyklonal

Konjugat

  • 17
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NANOS2 Antikörper ist unkonjugiert

Applikation

  • 19
  • 16
  • 4
  • 3
  • 2
  • 2
ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
  • Bindungsspezifität

    • 8
    • 7
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Aufreinigung

    Nanos2 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    Nanos2 antibody was raised against a 13 amino acid synthetic peptide near the amino terminus of the human Nanos2. The immunogen is located within the first 50 amino acids of Nanos2.

    Isotyp

    IgG
  • Applikationshinweise

    Nanos2 antibody can be used for detection of Nanos2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    Nanos2 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    Nanos2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    NANOS2 (Nanos Homolog 2 (NANOS2))

    Andere Bezeichnung

    Nanos2

    Hintergrund

    Nanos2 Antibody: Nanos is a zinc-finger containing, RNA-binding protein that has been implicated in germ cell development in both invertebrates and vertebrates. In Drosophila, Nanos represses apoptosis during development to ensure proper germ-line development. Unlike Nanos1 whose expression in mice is dispensable, the Nanos2 and Nanos3 proteins are required for germ cell development. Nanos2-null primordial germ cells (PGCs) die only in the male gonads and show no defects in females, while Nanos3-null PGCs are lost during the migration stage regardless of sex. Nanos2 and Nanos3 have distinct expression patterns during embryo development, suggesting that these two proteins do not have redundant functions. However, expression of Nanos2 can at least partially replace Nanos3 function in a Nanos3-null background. Nanos3 expression can not rescue Nanos2-null defects. This Nanos2 antibody will not cross-react with either Nanos 1 or Nanos3.

    Gen-ID

    339345

    UniProt

    P60321

    Pathways

    Retinoic Acid Receptor Signaling Pathway, Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance
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