VGF Antikörper (C-Term)

Produktnummer ABIN6990908

Der Kaninchen Polyklonal Anti-VGF-Antikörper wurde für WB, ELISA, IHC (p) und IF validiert. Er ist geeignet, VGF in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für VGF Antikörper (C-Term) (ABIN6990908)

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VGF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Produktdetails anti-VGF Antikörper

Bindungsspezifität: C-Term

Aufreinigung: VGF Antibody is affinity chromatography purified via peptide column.

Immunogen: VGF antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of the human VGF. The immunogen is located within the last 50 amino acids of VGF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: VGF antibody can be used for detection of VGF by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: VGF Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: VGF antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu VGF

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Andere Bezeichnung: VGF

Hintergrund: VGF Antibody: VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.

Molekulargewicht: Predicted: 68 kDa

Observed: 70 kDa 

Gen-ID: 7425

NCBI Accession: NP_003369

UniProt: O15240

Pathways: Hormone Transport, Carbohydrate Homeostasis