VGF Antikörper (C-Term)

Produktnummer ABIN501116

Der Kaninchen Polyklonal anti-VGF Antikörper wird verwendet zum Nachweis von VGF in Proben von Human, Ratte und Maus. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für VGF Antikörper (C-Term) (ABIN501116)

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VGF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-VGF Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects VGF.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography

Immunogen: VGF antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human VGF.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Details zu VGF

Target: VGF (VGF Nerve Growth Factor Inducible (VGF))

Andere Bezeichnung: VGF

Hintergrund: VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.Synonyms: Neurosecretory protein VGF

Gen-ID: 7425

NCBI Accession: NP_003369

Pathways: Hormone Transport, Carbohydrate Homeostasis