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ATG10 Antikörper (C-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ATG10 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN6990826

Kurzübersicht für ATG10 Antikörper (C-Term) (ABIN6990826)

Target

Alle ATG10 Antikörper anzeigen
ATG10 (Autophagy Related 10 (ATG10))

Reaktivität

  • 61
  • 14
  • 6
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 59
  • 1
  • 1
Kaninchen

Klonalität

  • 58
  • 3
Polyklonal

Konjugat

  • 27
  • 5
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ATG10 Antikörper ist unkonjugiert

Applikation

  • 25
  • 21
  • 20
  • 13
  • 13
  • 8
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 7
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term

    Aufreinigung

    ATG10 Antibody is affinity chromatography purified via peptide column.

    Immunogen

    ATG10 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human ATG10. The immunogen is located within the last 50 amino acids of ATG10.

    Isotyp

    IgG
  • Applikationshinweise

    ATG10 antibody can be used for the detection of ATG10 by Western blot at 0.5 - 2 μ,g/mL.

    Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    ATG10 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    ATG10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    ATG10 (Autophagy Related 10 (ATG10))

    Andere Bezeichnung

    ATG10

    Hintergrund

    ATG10 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. Another member of the autophagy protein family is ATG10, an E2-like enzyme involved in two ubiquitin-like modifications essential for autophagosome formation: ATG12-ATG5 conjugation and the modification of a soluble form of MAP-LC3, a homolog of yeast Apg8, to a membrane-bound form. ATG10 has also been shown to interact with ATG12 in human embryonic kidney cells in the presence of ATG7. Multiple isoforms of ATG10 are known to exist.

    Gen-ID

    83734

    UniProt

    Q9H0Y0

    Pathways

    ER-Nucleus Signaling, Autophagie
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