PTK7 Antikörper (C-Term)

Produktnummer ABIN6990782

Der Kaninchen Polyklonal Anti-PTK7-Antikörper wurde für WB, ELISA, IF und IHC (p) validiert. Er ist geeignet, PTK7 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für PTK7 Antikörper (C-Term) (ABIN6990782)

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PTK7 Antikörper

Bindungsspezifität: AA 880-930, C-Term

Aufreinigung: PTK7 Antibody is affinity chromatography purified via peptide column.

Immunogen: PTK7 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human PTK7. The immunogen is located within amino acids 880 - 930 of PTK7.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: PTK7 antibody can be used for detection of PTK7 by Western blot at 1 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PTK7 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: PTK7 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu PTK7

Target: PTK7 (PTK7 Protein tyrosine Kinase 7 (PTK7))

Andere Bezeichnung: PTK7

Hintergrund: PTK7 Antibody: Protein-tyrosine kinases (PTKs) play important roles in regulating cell proliferation and differentiation during development. One member of the PTK family, PTK7, has been suggested to regulate the planar cell polarity (PCP) pathway in vertebrates and may play a role in neural convergent extension and neural tube closure. PTK7 has also been implicated in the development of cancer. Loss of PTK7 expression was seen in several melanoma cell lines and biopsies. Conversely, high-throughput analysis of acute myeloid leukemia samples showed an increased level of PTK7 expression compared to normal bone marrow and purified CD34+ cells. Multiple isoforms of PTK7 are known to exist.

Gen-ID: 5754

UniProt: Q13308

Pathways: RTK Signalweg, Tube Formation