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Stim2 Antikörper (AA 140-190)

Stim2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990746
  • Target Alle Stim2 Antikörper anzeigen
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Bindungsspezifität
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 140-190
    Reaktivität
    • 37
    • 13
    • 8
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 35
    • 1
    • 1
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 21
    • 5
    • 4
    • 3
    • 2
    • 2
    Dieser Stim2 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 26
    • 19
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    STIM2 Antibody is affinity chromatography purified via peptide column.
    Immunogen
    STIM2 antibody was raised against a 17 amino acid synthetic peptide from near the center of human STIM2. The immunogen is located within amino acids 140 - 190 of STIM2.
    Isotyp
    IgG
    Top Product
    Discover our top product Stim2 Primärantikörper
  • Applikationshinweise
    STIM2 antibody can be used for detection of STIM2 by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 2.5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    STIM2 Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    STIM2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    Andere Bezeichnung
    STIM2 (Stim2 Produkte)
    Synonyme
    STIM2 antikoerper, stromal interaction molecule 2 antikoerper, STIM2 antikoerper, stim2 antikoerper, Stim2 antikoerper
    Hintergrund
    STIM2 Antibody: In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.
    Gen-ID
    57620
    NCBI Accession
    NP_065911
    UniProt
    Q9P246
    Pathways
    T-Zell Rezeptor Signalweg, BCR Signaling
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