CD180 Antikörper (C-Term)

Produktnummer ABIN6990644

Der Kaninchen Polyklonal Anti-CD180-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, CD180 in Proben von Human und Maus zu detektieren.

Kurzübersicht für CD180 Antikörper (C-Term) (ABIN6990644)

Target: CD180 (CD180 Molecule (CD180))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD180 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CD180 Antikörper

Bindungsspezifität: AA 590-640, C-Term

Aufreinigung: RP105 Antibody is affinity chromatography purified via peptide column.

Immunogen: RP105 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human RP105. The immunogen is located within amino acids 590 - 640 of RP105.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RP105 antibody can be used for the detection of RP105 by Western blot at 0.5 - 1 μ,g/mL. Despite its predicted molecular weight, RP105 often migrates at 95 - 105 kDa. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunohistochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RP105 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RP105 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CD180

Target: CD180 (CD180 Molecule (CD180))

Andere Bezeichnung: RP105

Hintergrund: RP105 Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins. One such protein is RP105, a recently identified homolog to TLR4 that, with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway. It has also been suggested that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.

Gen-ID: 4064

UniProt: Q99467

Pathways: Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades