TIMD4 Antikörper (C-Term)

Produktnummer ABIN6990639

Dieses Anti-TIMD4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TIMD4 in ELISA und WB. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TIMD4 Antikörper (C-Term) (ABIN6990639)

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIMD4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-TIMD4 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: TIM-4 Antibody is affinity chromatography purified via peptide column.

Immunogen: TIM-4 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human TIM-4. The immunogen is located within the last 50 amino acids of TIM-4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TIM-4 antibody can be used for the detection of TIM-4 by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TIM-4 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TIM-4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TIMD4

Target: TIMD4 (T-Cell Immunoglobulin and Mucin Domain Containing 4 (TIMD4))

Andere Bezeichnung: TIM-4

Hintergrund: TIM-4 Antibody: The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.

Gen-ID: 91937

NCBI Accession: NP_612388

UniProt: Q96H15

Pathways: Cancer Immune Checkpoints