TOLLIP Antikörper (AA 70-120)

Produktnummer ABIN6990611

Der Kaninchen Polyklonal Anti-TOLLIP-Antikörper wurde für WB, ELISA und ICC validiert. Er ist geeignet, TOLLIP in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für TOLLIP Antikörper (AA 70-120) (ABIN6990611)

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOLLIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-TOLLIP Antikörper

Bindungsspezifität: AA 70-120

Aufreinigung: TOLLIP Antibody is affinity chromatography purified via peptide column.

Immunogen: TOLLIP antibody was raised against a 16 amino acid synthetic peptide from near the center of human TOLLIP. The immunogen is located within amino acids 70 - 120 of TOLLIP.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: TOLLIP antibody can be used for the detection of TOLLIP by Western blot at 0.5 - 2 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 2 μ,g/mL.

Antibody validated: Western Blot in rat samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: TOLLIP Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: TOLLIP antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TOLLIP

Target: TOLLIP (Toll Interacting Protein (TOLLIP))

Andere Bezeichnung: TOLLIP

Hintergrund: TOLLIP Antibody: Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.

Gen-ID: 54472

UniProt: Q9H0E2