BCL2L1 Antikörper (C-Term)

Produktnummer ABIN6990472

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BCL2L1 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BCL2L1 Antikörper (C-Term) (ABIN6990472)

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-BCL2L1 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Bcl-xL Antibody is supplied as ion exchange chromatography purified IgG.

Immunogen: Bcl-xL antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bcl-xL. The immunogen is located within the last 50 amino acids of Bcl-xL.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Bcl-xL antibody can be used for detection of Bcl-xL by Western blot at 1 to 2 μ,g/mL.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Bcl-xL Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Bcl-xL antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu BCL2L1

Target: BCL2L1 (BCL2-Like 1 (BCL2L1))

Andere Bezeichnung: Bcl-xL

Hintergrund: Bcl-xL Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. Bcl-xL is a member of the Bcl-2 family of proteins that are critical regulators of apoptosis. These can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bcl-xL is an anti-apoptotic mitochondrial protein related to Bcl-w and the major transcript of the bcl-x gene. Its high expression in tumors is correlated with advanced disease and poor prognosis. Bcl-xL expression level increases in response to several stimuli such as ionizing radiation and treatment with chemotherapeutic agents.

Gen-ID: 598

UniProt: Q07817

Pathways: Apoptose, Negative Regulation of intrinsic apoptotic Signaling