BCL2L10 Antikörper (N-Term)

Produktnummer ABIN6990431

Der Kaninchen Polyklonal Anti-BCL2L10-Antikörper wurde für WB, ELISA und ICC validiert. Er ist geeignet, BCL2L10 in Proben von Human zu detektieren.

Kurzübersicht für BCL2L10 Antikörper (N-Term) (ABIN6990431)

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2L10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-BCL2L10 Antikörper

Bindungsspezifität: AA 90-140, N-Term

Aufreinigung: Bcl-B Antibody is affinity chromatography purified via peptide column.

Immunogen: Bcl-B antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human Bcl-B. The immunogen is located within amino acids 90 - 140 of Bcl-B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Bcl-B antibody can be used for the detection of Bcl-B by Western blot at 1 - 2 μ,g/mL. Despite its predicted molecular weight, Bcl-B is often at higher molecular weights, presumably due to post-translational modifications. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Bcl-B Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Bcl-B antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu BCL2L10

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Andere Bezeichnung: Bcl-B

Hintergrund: Bcl-B Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-B is a recently discovered anti-apoptotic member of the Bcl-2. Unlike the mouse homolog (also known as Diva/Boo) which is predominantly expressed in ovary and testis, the human Bcl-B protein is widely expressed. Also, the human Bcl-B functions by binding to and suppressing the apoptotic activity of Bax, whereas the mouse homolog binds Bak and also interacts with the apoptosis protein Apaf-1.

Molekulargewicht: Predicted: 22 kDa

Observed: 26 kDa

Gen-ID: 10017

NCBI Accession: NP_065129

UniProt: Q9HD36

Pathways: Positive Regulation of Endopeptidase Activity