BCL2L10 Antikörper (AA 31-186)

Produktnummer ABIN5611302

Produktdetails anti-BCL2L10 Antikörper

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Bindungsspezifität: AA 31-186

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser BCL2L10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human BCL2L10 (AA: 31-186) expressed in E. coli.

Klon: 8A2F9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu BCL2L10

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Andere Bezeichnung: BCL2L10 (BCL2L10 Produkte)

Synonyme: BCL-B antikoerper, Boo antikoerper, Diva antikoerper, AA420380 antikoerper, AU023065 antikoerper, C85687 antikoerper, NR-13 antikoerper, mcl1l antikoerper, nr13 antikoerper, sb:cb78 antikoerper, BCL2 like 10 antikoerper, Bcl2-like 10 antikoerper, BCL2-like 10 (apoptosis facilitator) antikoerper, BCL2L10 antikoerper, Bcl2l10 antikoerper, bcl2l10 antikoerper

Hintergrund:

Description: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Aliases: Boo, Diva, BCL-B, bcl2-L-10

Molekulargewicht: 22 kDa

Gen-ID: 10017

HGNC: 10017

Pathways: Positive Regulation of Endopeptidase Activity