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CARD10 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-CARD10-Antikörper wurde für WB, ELISA, IF und ICC validiert. Er ist geeignet, CARD10 in Proben von Human und Maus zu detektieren.
Produktnummer ABIN6990395

Kurzübersicht für CARD10 Antikörper (C-Term) (ABIN6990395)

Target

Alle CARD10 Antikörper anzeigen
CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

Reaktivität

  • 29
  • 6
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 29
  • 1
Kaninchen

Klonalität

  • 29
  • 1
Polyklonal

Konjugat

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CARD10 Antikörper ist unkonjugiert

Applikation

  • 18
  • 14
  • 6
  • 5
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Aufreinigung

    CARD10 Antibody is immunoaffinity purified .

    Immunogen

    CARD10 antibody was raised against a synthetic peptide corresponding to 14 amino acids at the C-terminus of human CARD10. The immunogen is located within the last 50 amino acids of CARD10.

    Isotyp

    IgG
  • Applikationshinweise

    CARD10 antibody can be used for detection of CARD10 by Western blot at 5 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

    Antibody validated: Western Blot in mouse samples, Immunocytochemistry in mouse samples and Immunofluorescence in mouse samples. All other applications and species not yet tested.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    CARD10 Antibody is supplied in PBS containing 0.02 % sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,4 °C

    Informationen zur Lagerung

    CARD10 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target

    CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))

    Andere Bezeichnung

    CARD10

    Hintergrund

    CARD10 Antibody: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, Bcl-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD10. This protein belongs to the membrane-associated guanylate kinase-like (MAGUK) family of proteins that can function as molecular scaffolds that assist assembly of signal transduction molecules. CARD 10 interacts with Bcl-10, a Bcl protein that promotes apoptosis, caspase-9 maturation and activation of NF-κ,B. CARD 10 and the related protein CARMA1 also associate with NEMO, the regulatory subunit of the Iκ,K complex, demonstrating its importance in the regulation of NF-κ,B transcription factor activation.

    Molekulargewicht

    Predicted: 116 kDa

    Observed: 115 kDa

    Gen-ID

    29775

    UniProt

    Q9BWT7

    Pathways

    S100 Proteine
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