CARD10 Antikörper (AA 863-1032)
Kurzübersicht für CARD10 Antikörper (AA 863-1032) (ABIN6137937)
Target
Alle CARD10 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 863-1032
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Sequenz
- LLDLPSSRLD FQVCPAESLS GEELCPSSAP GAPKAQPATP GLGSRIRAIQ ESVGKKHCLL ELGARGVREL VQNEIYPIVI HVEVTEKNVR EVRGLLGRPG WRDSELLRQC RGSEQVLWGL PCSWVQVPAH EWGHAEELAK VVRGRILQEQ ARLVWVECGS SRGCPSSSEA
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 863-1032 of human CARD10 (NP_055365.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CARD10 (Caspase Recruitment Domain Family, Member 10 (CARD10))
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Andere Bezeichnung
- CARD10
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Hintergrund
- The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB, see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM, Mar 2008],CARD10,BIMP1,CARMA3,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD10
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Molekulargewicht
- 82 kDa/115 kDa
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Gen-ID
- 29775
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UniProt
- Q9BWT7
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Pathways
- S100 Proteine
Target
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