TRAF3IP2 Antikörper (C-Term)

Produktnummer ABIN6990384

Dieses Anti-TRAF3IP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRAF3IP2 in WB, ELISA, IF und IHC (p). Geeignet für Human.

Kurzübersicht für TRAF3IP2 Antikörper (C-Term) (ABIN6990384)

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF3IP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TRAF3IP2 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: CIKS Antibody is affinity chromatography purified via peptide column.

Immunogen: CIKS antibody was raised against a 15 amino acid peptide near the carboxy terminus of human CIKS. The immunogen is located within the last 50 amino acids of CIKS.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CIKS antibody can be used for detection of CIKS by Western blot at 1 μ,g/mL. A band at approximately 63 kDa can be detected. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CIKS Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CIKS antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu TRAF3IP2

Target: TRAF3IP2 (TRAF3 Interacting Protein 2 (TRAF3IP2))

Andere Bezeichnung: CIKS

Hintergrund: CIKS Antibody: Nuclear factor kappa B (NF-κ,B) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κ,B mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κ,B associates with Iκ,B proteins in the cell cytoplasm, which inhibit NF-κ,B activity. Iκ,B is phosphorylated by Iκ,B kinase (IKK) complex that contains IKKα, IKKβ, and IKKγ,. A novel molecule that associates with and activates IKK was recently identified and designated CIKS (for connection to IKK and SAPK/JNK) and Act1 (for NF-κ,B activator 1). CIKS directly interacts with IKKγ,. CIKS/Act1 also activates activating transcription factor (ATF) and activator protein 1 (AP-1) through Jun kinase (JNK). These results indicate that CIKS/Act1 is involved in the inflammation and stress responses. CIKS/Act1 is ubiquitously expressed in human tissues.

Molekulargewicht: 63 kDa

Gen-ID: 10758

UniProt: O43734

Pathways: Production of Molecular Mediator of Immune Response