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IL22R Antikörper (N-Term)

IL22R Reaktivität: Human, Ratte WB, ICC, ELISA, IHC (p), IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6990383
  • Target Alle IL22R Produkte
    IL22R (Interleukin 22 Receptor (IL22R))
    Bindungsspezifität
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 9
    • 3
    • 2
    Human, Ratte
    Wirt
    • 10
    • 2
    Kaninchen
    Klonalität
    • 12
    Polyklonal
    Konjugat
    • 11
    • 1
    Dieser IL22R Antikörper ist unkonjugiert
    Applikation
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Aufreinigung
    IL-22 Receptor Antibody is affinity chromatography purified via peptide column.
    Immunogen
    IL-22 receptor antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human IL-22 receptor precursor. The immunogen is located within the first 50 amino acids of IL-22 Receptor.
    Isotyp
    IgG
  • Applikationshinweise
    IL-22 receptor antibody can be used for detection of IL-22 receptor by Western blot at 0.5-1 μ,g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ,g/mL and immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 10 μ,g/mL.               

    Antibody validated: Western Blot in human samples, Immunohistochemistry in rat samples, Immunocytochemistry in human samples and Immunofluorescence in human and rat samples. All other applications and species not yet tested.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    IL-22 Receptor Antibody is supplied in PBS containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C,4 °C
    Informationen zur Lagerung
    IL-22 Receptor antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Target
    IL22R (Interleukin 22 Receptor (IL22R))
    Andere Bezeichnung
    IL-22 Receptor (IL22R Produkte)
    Hintergrund
    IL-22 Receptor Antibody: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified. The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family. IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling. IL-22 and its receptor activate JAK-STAT signaling pathway. IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10. A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently. IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity. LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
    Molekulargewicht
    Predicted: 63 kDa

    Observed: 65 kDa
    Gen-ID
    58985
    NCBI Accession
    NP_067081
    UniProt
    Q8N6P7
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