IL22R Antikörper (AA 560-574)

Produktnummer ABIN1886889

Produktdetails anti-IL22R Antikörper

Target: IL22R (Interleukin 22 Receptor (IL22R))

Bindungsspezifität: AA 560-574

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL22R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: Synthetic peptide corresponding to amino acids 560 to 574 of human IL-22 receptor precursor.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid freezing and thawing repeatly.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Details zu IL22R

Target: IL22R (Interleukin 22 Receptor (IL22R))

Abstract: IL22R Produkte

Hintergrund: A novel cytokine, designated IL-TIF for IL-10 related T cell-derived inducible factor and IL-22, was recently identified.The receptor for IL-22 (IL-22R, also termed CRF2-9 and IL-TIF-R1 chain) is a new member of the class II cytokine receptor family.IL-22R forms a complex with IL-10 receptor beta chain and mediates IL-22 signaling.IL-22 and its receptor activate JAK-STAT signaling pathway.IL22R is expressed in normal liver and kidney and their cell lines HepG2 and TK-10.A soluble form of IL-22 receptor, also termed IL-22 binding protein (IL-22BP) and IL-22 receptor-alpha 2 (IL-22RA2), was identified very recently.IL-22BP prevents binding of IL-22 to the functional cell surface IL-22R complex and neutralizes IL-22 activity.LPS induces IL-22 expression, which indicates the role of IL-22 in inflammatory response.
Synonyms: IL22R

Molekulargewicht: 62 kDa