Caspase 4 Antikörper (N-Term)

Produktnummer ABIN6990327

Dieses Anti-Caspase 4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Caspase 4 in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für Caspase 4 Antikörper (N-Term) (ABIN6990327)

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Caspase 4 Antikörper

Bindungsspezifität: AA 80-130, N-Term

Aufreinigung: Caspase-13 Antibody is Ion exchange chromatography purified.

Immunogen: Caspase-13 antibody was raised against a 15 amino acid peptide near the amino terminus of bovine Caspase-13. The immunogen is located within amino acids 80 - 130 of Caspase-13.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Caspase-13 antibody can be used for detection of caspase-13 by Western blot at 1 μ,g/mL. A 43 kDa band should be detected. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Caspase-13 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Caspase-13 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu Caspase 4

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Andere Bezeichnung: Caspase-13

Hintergrund: Caspase-13 Antibody: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death is finally caused by members of the caspase family of proteases and caspase activated DNases. A novel member in the caspase family was recently identified and designated ERICE (for Evolutionarily Related Interleukin-1 beta Converting Enzyme) and caspase-13. Caspase-13 belongs to the ICE subfamily of caspases. Overexpression of caspase-13 induces apoptosis. Caspase-13 was activated by caspase-8, which is a key enzyme in death receptor induced apoptosis. Caspase-13 is expressed in a variety of human tissues and cell lines.

Molekulargewicht: 43 kDa

Gen-ID: 338039

UniProt: O75601

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity