CCR8 Antikörper (AA 170-220)

Produktnummer ABIN6990287

Der Kaninchen Polyklonal Anti-CCR8-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, CCR8 in Proben von Human zu detektieren.

Kurzübersicht für CCR8 Antikörper (AA 170-220) (ABIN6990287)

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CCR8 Antikörper

Bindungsspezifität: AA 170-220

Aufreinigung: CCR8 Antibody is affinity chromatography purified via peptide column.

Immunogen: CCR8 antibody was raised against a 19 amino acid peptide near the center of human CCR8. The immunogen is located within amino acids 170 - 220 of CCR8.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: CCR8 antibody can be used for detection of CCR8 by Western blot 0.5 μ,g/mL. An approximately 50 kDa band can be detected.

Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: CCR8 Antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: CCR8 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Details zu CCR8

Target: CCR8 (Chemokine (C-C Motif) Receptor 8 (CCR8))

Andere Bezeichnung: CCR8

Hintergrund: CCR8 Antibody: CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.

Molekulargewicht: 50 kDa

Gen-ID: 1237