GAPDH Antikörper (C-Term) (Biotin)

Produktnummer ABIN6990220

Dieses Maus Monoklonal-Antikörper erkennt spezifisch GAPDH in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte und Kaninchen.

Kurzübersicht für GAPDH Antikörper (C-Term) (Biotin) (ABIN6990220)

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Reaktivität: Human, Maus, Ratte, Kaninchen

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GAPDH Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Klon: 12D3D5

Produktdetails anti-GAPDH Antikörper (Biotin)

Bindungsspezifität: C-Term

Spezifität: Biotin-GAPDH antibody is human, mouse, rat, and rabbit reactive.

Aufreinigung: Biotin-GAPDH antibody is Protein A purified.

Immunogen: Biotin-GAPDH antibody was raised against a 16 amino acid peptide near the carboxy terminus of human GAPDH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Biotin-GAPDH antibody can be used for detection of GAPDH by Western blot at 1 - 2 μ,g/mL.

Antibody validated: Western Blot in human, mouse, and rat samples. All other applications and species not yet tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Biotin-GAPDH antibody is supplied in PBS containing 1 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: Biotin-GAPDH antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu GAPDH

Target: GAPDH (Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH))

Andere Bezeichnung: GAPDH

Hintergrund: Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD), an important energy-yielding step in carbohydrate metabolism. It also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH also plays a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer's and Huntington's disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.

Molekulargewicht: Predicted: 37 kDa

Observed: 36 kDa

Gen-ID: 2597

NCBI Accession: NP_002037

UniProt: P04406