ARNT Antikörper

Produktnummer ABIN6989933

Der Kaninchen Monoklonal Anti-ARNT-Antikörper wurde für WB, IHC und IHC (p) validiert. Er ist geeignet, ARNT in Proben von Human zu detektieren.

Kurzübersicht für ARNT Antikörper (ABIN6989933)

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser ARNT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 11H1

Produktdetails anti-ARNT Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu ARNT

Target: ARNT (Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))

Andere Bezeichnung: HIF-1 beta

Hintergrund:

Synonyms: arnT antibody, ARNT protein antibody, ARNT_HUMAN antibody, Aryl hydrocarbon receptor nuclear translocator antibody, bHLHe2 antibody, Class E basic helix-loop-helix protein 2 antibody, Dioxin receptor antibody, Dioxin receptor nuclear translocator antibody, Drnt antibody, HIF 1 beta antibody, HIF 1beta antibody, HIF-1-beta antibody, HIF1-beta antibody, HIF1B antibody, HIF1beta antibody, Hypoxia Inducible Factor 1 antibody, Hypoxia inducible factor 1 beta antibody, Hypoxia-inducible factor 1-beta antibody, nuclear translocator antibody, Tango antibody

Background: This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gen-ID: 405

UniProt: P27540

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt