LITAF Antikörper
Kurzübersicht für LITAF Antikörper (ABIN6989826)
Target
Alle LITAF Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Kreuzreaktivität
- Human, Maus
- 
                                            Aufreinigung
- Purified by Protein A.
- 
                                            Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-161 of human LITAF (NP_004853.2).
- 
                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- 
                        WB 1:300-5000
 IHC-P 1:200-400
 IP(1-2 μg)
 IHC()
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 1 μg/μL
- 
                                            Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            Konservierungsmittel
- ProClin
- 
                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 
                                            Lagerung
- -20 °C
- 
                                            Informationen zur Lagerung
- Store at -20°C for 12 months.
- 
                                            Haltbarkeit
- 12 months
 
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    - LITAF (Lipopolysaccharide-Induced Tumor Necrosis Factor-alpha Factor (LITAF))
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                                            Andere Bezeichnung
- LITAF
- 
                                            Hintergrund
- 
                        Synonyms: LITAF,PIG7,SIMPLE,TP53I7 Background: Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppressor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD). Multiple alternatively spliced transcript variants have been found for this gene. 
- 
                                            Gen-ID
- 9516
- 
                                            UniProt
- Q99732
- 
                                            Pathways
- Cellular Response to Molecule of Bacterial Origin
 Target
- 
                    
 
                                     
                                     
                                    