YAP1 Antikörper (pSer127)

Produktnummer ABIN6989717

Der Kaninchen Monoklonal Anti-YAP1-Antikörper wurde für FACS und IHC (p) validiert. Er ist geeignet, YAP1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für YAP1 Antikörper (pSer127) (ABIN6989717)

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser YAP1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 1H12

Produktdetails anti-YAP1 Antikörper

Bindungsspezifität: pSer127

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Synthetic peptide derived from human YAP1 (S127), around 100-150aa (phospho S127).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu YAP1

Target: YAP1 (Yes-Associated Protein 1 (YAP1))

Andere Bezeichnung: YAP1

Hintergrund:

Synonyms: 65 kDa Yes associated protein, YAp 1, YAp-1, YAP 65, YAP, YAP2, YAP65, Yes associated protein 1 65 kDa, Yes associated protein 1, Yes associated protein 2, YKI.

Background: YAP1 (also known as Yes associated protein 1) was originally identified as a transcription factor that binds to the SH3 domain of the YES kinase (a Src protein kinase). More recently it has been identified as a candidate oncogene that promotes tumorigenesis in many different types of cancer.

Gen-ID: 10413

UniProt: P46937

Pathways: MAPK Signalweg, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha