CTNNA3 Antikörper

Produktnummer ABIN6989713

Dieses Kaninchen Monoklonal-Antikörper erkennt spezifisch CTNNA3 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CTNNA3 Antikörper (ABIN6989713)

Target: CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser CTNNA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 3H55

Produktdetails anti-CTNNA3 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant fragment within C-terminal Human CTNNA3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu CTNNA3

Target: CTNNA3 (Catenin (Cadherin-Associated Protein), alpha 3 (CTNNA3))

Andere Bezeichnung: CTNNA3

Hintergrund:

Synonyms: 4930429L08Rik antibody, 4933408A16 antibody, Alpha catenin like protein antibody, Alpha T catenin antibody, Alpha T-catenin antibody, Cadherin associated protein antibody, Cadherin-associated protein antibody, Catenin alpha 3 antibody, Catenin alpha-3 antibody, Catna3 antibody, CTNA3_HUMAN antibody, CTNNA3 antibody, MGC26194 antibody, MGC75041 antibody, OTTHUMP00000019684 antibody, OTTMUSP00000028119 antibody, OTTMUSP00000028120 antibody, RP11-433J16.1 antibody, VR22 antibody

Background: The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy.

Gen-ID: 29119

UniProt: Q9UI47