STK39 Antikörper

Produktnummer ABIN6989664

Dieses Anti-STK39-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von STK39 in WB, IHC (p) und FACS. Geeignet für Human.

Kurzübersicht für STK39 Antikörper (ABIN6989664)

Target: STK39 (serine threonine Kinase 39 (STK39))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser STK39 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Klon: 6H14

Produktdetails anti-STK39 Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Synthetic Peptide corresponding to C terminal human SPAK.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu STK39

Target: STK39 (serine threonine Kinase 39 (STK39))

Andere Bezeichnung: SPAK

Hintergrund:

Synonyms: DCHT antibody, DKFZp686K05124 antibody, OTTHUMP00000165175 antibody, PASK antibody, Proline alanine rich STE20 related kinase antibody, Serine threonine kinase 39 (STE20/SPS1 homolog yeast) antibody, Serine threonine kinase 39 antibody, Serine/threonine protein kinase 39 antibody, Serine/threonine-protein kinase 39 antibody, Small intestine SPAK like kinase antibody, SPAK antibody, Ste 20 related kinase antibody, Ste-20-related kinase antibody, Ste20 like protein kinase antibody, STE20/SPS1 homolog antibody, STE20/SPS1 related proline alanine rich protein kinase antibody, STE20/SPS1-related proline-alanine-rich protein kinase antibody, STK 39 antibody, Stk39 antibody, STK39_HUMAN antibody

Background: The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. SPAK, also known as STK39 (serine threonine kinase 39), DCHT or PASK, is a 547 amino acid protein that localizes to both the cytoplasm and the nucleus and contains one protein kinase domain. Expressed predominately in pancreas, brain, heart, lung, liver and testis, SPAK functions as a Ser/Thr protein kinase that catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in mediating stress-activated signals. The gene encoding SPAK maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8 % of the human genome.

Gen-ID: 27347

UniProt: Q9UEW8