Thyroglobulin Antikörper

Produktnummer ABIN6989610

Dieses Anti-Thyroglobulin-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von Thyroglobulin in IHC, WB und IHC (p). Geeignet für Human.

Kurzübersicht für Thyroglobulin Antikörper (ABIN6989610)

Target: Thyroglobulin (TG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Thyroglobulin Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: 2H4

Produktdetails anti-Thyroglobulin Antikörper

Kreuzreaktivität: Human

Aufreinigung: Purified by Protein A.

Immunogen: Recombinant protein within C-terminal human Thyroglobulin.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Thyroglobulin

Target: Thyroglobulin (TG)

Andere Bezeichnung: Thyroglobulin

Hintergrund:

Synonyms: AITD 3 antibody, AITD3 antibody, hTG antibody, TDH3 antibody, Tg antibody, TGN antibody, THYG_HUMAN antibody, Thyroglobulin antibody

Background: Thyroglobulin is the glycoprotein precursor of the iodinated thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is obtained from the thyroid gland and exhibits the general properties of the globulins. The human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti thyroglobulin autoantibodies were the first factor to be discovered. Anti hTG is found in all thyroid autoimmune diseases (Hashimoto's thyroiditis, Graves' diseases), with the highest level observed in Hashimoto's thyroiditis. Anti hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

Gen-ID: 7038

UniProt: P01266

Pathways: Thyroid Hormone Synthesis