TUBA1B Antikörper (AA 401-451)

Produktnummer ABIN6989271

Dieses Anti-TUBA1B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TUBA1B in WB, ELISA, IF, IHC (p), IF (cc) und IHC (fro). Geeignet für Human, Maus und Ratte.

Kurzübersicht für TUBA1B Antikörper (AA 401-451) (ABIN6989271)

Target: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TUBA1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TUBA1B Antikörper

Bindungsspezifität: AA 401-451

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TUBA1A + TUBA1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(ICC) 1:50-200
IF()

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TUBA1B

Target: TUBA1B (Tubulin, alpha 1B (TUBA1B))

Andere Bezeichnung: TUBA1A + TUBA1B

Hintergrund:

Synonyms: TUBA1A + TUBA1B, Tubulin, Alpha 1b, Tubulin Alpha-Ubiquitous Chain, Alpha-Tubulin Ubiquitous, Tubulin K-Alpha-1, Tubulin, Alpha, Ubiquitous, Tubulin Alpha-1B Chain, Alpha Tubulin, Ubiquitous, K-ALPHA-1, Tubulin Alpha, TBA1B_HUMAN, Tubulin, Alpha 1a, TUBA3, Tubulin Alpha-3 Chain, Tubulin B-Alpha-1, LIS3, Tubulin, Alpha, Brain-Specific, Tubulin Alpha-1A Chain, Alpha-Tubulin 3, Brain-Specific, Hum-A-Tub1, Hum-A-Tub2, B-ALPHA-1, TBA1A_HUMAN, ,____alpha

Background: Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]

Gen-ID: 7846

UniProt: Q71U36

Pathways: Microtubule Dynamics, M Phase