TOP2B Antikörper (AA 1-100)

Produktnummer ABIN6989203

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TOP2B in IHC (p), IF (cc), IF (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TOP2B Antikörper (AA 1-100) (ABIN6989203)

Target: TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOP2B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-TOP2B Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: Topoisomerase II beta Polyclonal Antibody

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Chimpanzee

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Topoisomerase II beta

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu TOP2B

Target: TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))

Andere Bezeichnung: Topoisomerase II beta

Hintergrund:

Synonyms: Antigen MLAA 44, beta isozyme, DNA topoisomerase 2 beta, DNA topoisomerase 2-beta, DNA topoisomerase II 180 kD, DNA topoisomerase II, DNA topoisomerase II beta, DNA topoisomerase II beta isozyme, Top 2, TOP 2B, TOP IIB, Top2 beta, TOP2B, TOP2B_HUMAN, Top2beta, TOPIIB, Topo II beta, Topoisomerase (DNA) II beta 180 kDa, Topoisomerase (DNA) II beta, Topoisomerase IIb, U937 associated antigen.

Background: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Gen-ID: 7155

UniProt: Q02880